Luận văn Thạc sĩ Khoa học: Nghiên cứu các xanthanolid và các thành phần hóa học khác của cây Ké đầu ngựa (Xanhthium strumarium L., Asteraceae) mọc ở Hà Nội
5,872
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Xanthium strumarium
c sau.
(Xanthium strumarium
n-hexan (XSLH,
h
XSLDn-
hexan (XSCH XSCD, 0,34 %).
9
n-
-MS,
1
H-NMR,
13
- DEPT).
3-hexacosanyl-2-oxacyclopentanon (I), -sitosterol (II), betulin
(III),
5,8-epidioxy-(22E,24R)-ergosta-6,22-dien-3-ol (IV), acid tricosanoic (V), N-
(1,3,4-trihydroxyheptadec-2-yl)-2-hydroxypentadecanamid (VIa N-(1,3,4-
trihydroxy-8Z-eicos-8-en-2-yl)-2-hydroxypentadecanamid (VIb), -sitosterol 3-O-
-D-glucopyranosid (VIIa) -O--D-glucopyranosid (VIIb)
; và -sitosterol (II), 1-tricosanol
(VIII)IX)
.
I, III, IV, V, VIa, VIb, VIIIIX
Xanthium strumariumVIa
VIb IX
cây Artermisia japonica m 2014)id
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th
10
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1. 2011),
,Tp 1, 456-458.
2. ,
Minh, 178-179.
3.91),
4.
-79.
nh
Xanthium
spinosumPhytochemistry, 23 (4), 915-916.
from Xanthium spinosum, Phytochemistry, 30 (10), 3461-3462.
Xanthium pungensPhytochemistry, 29 (7), 2211-2215.
8. Ahmed A. M., Ahmed A. A., Munekazu I., Toshiyuki T. (1995),
fruits of Xanthium
pungens
Terrahedron Letters, 36 (49), 8985-8986.
9. Anjoo K., Ajay Phytopharmacological review of Xanthium
strumarium L. (Cocklebur)Int. J. Green Pharm., 4 (3), 129-139.
Preliminary
evaluation
of in vitro cytotoxicity and in vivo antitumor activity of Xanthium strumarium
in
transplantable tumors in miceAm. J. Chin. Med., 41 (1), 145-162.
11. Bader A., Giner R. M., Martini F., Schinella G. R., Ríos J. L., Braca A.,
Prieto J.
M. Modulation of COX, LOX and NXanthium spinosum
L. root extract and ziniolideFitoterapia, 91, 284-289.
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66
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lactones from the
aerial
parts of Xanthium sibiricum and their cytotoxic effects on human cancer cell
lines
Phytochemistry Letters, 5, 685-689.
new thiazinedione glycoside from the fruit
of
Xanthium sibiricumChemistry of Natural Compounds, 49 (5), 977-979.
14. Cermak S. C., Isbell T. A. (2000), Synthesis of -stearolactone from oleic
acid, JAOCS, 74 (3), 243-248.
15. Elmira C., Riscala D., anthanolides and a bis-
norxanthanolide from Xanthium cavanillesiiPhytochemistry, 35 (6), 1588-1589.
16
Xanthium
orientalePhytochemistry, 20 (10), 2429-2430.
17. Fer
Xanthium
indicumPhytochemistry, 21 (6), 1441-1443.
18.
eudesmanes from Artemisia japonica Nat. Prod. Res., doi:
10.1080/14786419.2014.891115.
19
ldose
reductase inhibitory compounds from Xanthium strumarium Arch. Pharm. Res,
36, 1090-1095.
20 our
new
glycosides from the fruit of Xanthium sibiricum Molecules, 18, 12464-
12473.
21
-Tri-O-
caffeoylquinic acid from X, Phytochemistry, 33 (2), 508-509.
22. Jativa C., Xanthium
catharticum
J. Nat. Prod., 54 (2), 460-465.
23wo toxic kaurene glycosides from the burrs of
Xanthium pungensJ. Nat. Prod., 53 (2), 451-455.
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24. Kim Y. S., Kim J. S., Two cytotoxic
sesquiterpene lactones from the leaves of Xanthium strumarium and their in vitro
inhibitory activity on farnesyltransferasePlanta Med., 69 (4), 375-377.
25. Laura S. F., Alejandra O. M., Graciela H. W. (200Anti-ulcerogenic
activity
of xanthanolide sesquiterpenes from Xanthium cavanillesii , J.
Ethnopharmacol., 100, 260-267.
26. Lee C. L., Huang P. C., Hsieh P. W., Hwang T. L., Hou Y. Y. (2008), -)-
Xanthienopyran, a new inhibitor of superoxide anion generation by activated
neutrophils, and further constituents of the seeds of Xanthium
strumariumPlanta
Med., 74 (10), 1276-1279.
27Inhibition of melanogenesis
by Xanthium strumarium LBiosci. Biotechnol. Biochem., 76 (4), 767-771.
28 anthanolides
from
Xanthium strumariumPhytochemistry, 32 (1), 206-207.
29. Miemanang R. S.,
Paullinomide A: A new cerebroside and a new ceramide from leaves of Paullinia
pinnataZ. Naturforsch, 61b, 1123-1127.
30Biological activities
of
xanthatin from Xanthium strumarium Phytother Res., 25 (12), 1883-1890.
31 Xanthium
cavanillesiiNat. Prod. Res., 23 (4), 388-392.
32 Isolation and identification of
phytochemicals from Xanthium strumarium International J. Chem. Tech. Res., 4
(1), 266-271.
33. Parwaiz A., Mohd A., Maheesh P. S., Humaira F., Hamid N. K. (2010),
ts of Corylus colurna J. Phytol., 2
(3),
89-100.
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34. Ramisrez E. I., Huang Y., Hick
Xanthatin
and xanthinosin from the burs of Xanthium strumarium L. as potential anticancer
agentsCan. J. Physiol. Pharmacol., 85 (11), 1160-1172.
35 Xanthium
strumariumPhytochemistry, 35 (4), 1080-1082.
36
from Xanthium spinosumPhytochemistry, 41 (5), 1357-1360.
37. Takeda S., Matsuo K., Yaji K., Okajima M. (2011), -)-Xanthatin selectively
-independent cell death in human breast
cancer MDA-MB-231 cellsChem. Res. Toxicol., 24 (6), 855-865.
38. Toshie T., Yoshitsugu S. (1980), Structures of xantholides A and B, two new
guaianolides from Xanthium canadense Tetrahedron Letters, 21, 1861-1862.
39Anti-allergic rhinitis
effect of
caffeoylxanthiazonoside isolated from fruits of Xanthium strumarium L. in rodent
animalsPhytomedicine, 14, 21-26.
40. Yamasaki K., Sholichin M., Kasai R., Tanaka O. (1980),
13
C Nuclear magnetic
resonance of lupane- ,
Chem.
Pharm. Bull., 28(3), 1006-1008.
41 Inhibition of
lipopolysaccharide-
induced inducible nitric oxide synthase and cyclooxygenase-2 expression by
xanthanolides isolated from Xanthium strumarium Bioorganic & Medicinal
Chemistry Letters, 18, 2179-2182.
42. Ying T. M., Mu C. H., Feng L. H., Hsiu F. C. Thiazinedione from
Xanthium strumariumPhytochemistry, 48 (6), 1083-1085.
43. Yue M., Chen S. N., Lin Z. W., Sun H. D. (2001), Sterols from the fungus
Lactarium volemus, Phytochemistry, 56, 801-806.
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PH LC 1: PH
1
H-NMR CA XSLH4.1 (I)
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PH LC 2: PH
13
C-NMR VÀ DEPT CA XSLH4.1 (I)
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PH LC 3: PH (+)-ESI-MS CA XSLH4.1 (I)